A potent, selective 20-HETE synthase inhibitor
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CAY10462

Item No. 10006400

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-[4-(1H-imidazol-1-yl)phenoxy]-N,N-dimethyl-1-hexanamine, dihydrochloride
CAS Number
502656-68-0
Molecular Formula
C17H25N3O • 2HCl
Formula Weight
360.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 15 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
202, 246 nm
SMILES
CN(C)CCCCCCOC1=CC=C(N2C=CN=C2)C=C1.Cl.Cl
InChi Code
InChI=1S/C17H25N3O.2ClH/c1-19(2)12-5-3-4-6-14-21-17-9-7-16(8-10-17)20-13-11-18-15-20;;/h7-11,13,15H,3-6,12,14H2,1-2H3;2*1H
InChi Key
SRCWAJONAASSNJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $28

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    5 mg

    $118

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    10 mg

    $205

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    50 mg

    $888

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    Product Description

    CAY10462 is the hydrochloride salt of CAY10434 and selective inhibitor of the 20-HETE synthase CYP4A11 exhibiting an IC50 of 8.8 nM when tested in human renal microsomes.1 CAY10434 is nearly 200 times less potent as an inhibitor of 1A, 1C, and 3A CYP450 enzymes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nakamura, T., Kakinuma, H., Umemiya, H., et al. Imidazole derivatives as new potent and selective 20-HETE synthase inhibitor. Bioorg. Med. Chem. Lett. 14, 333-336 (2004).