Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…

Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

Estradiol

Cayman Chemical Item Number 10006315

17β-Oestradiol; 17β-Estradiol; β-Estradiol (CAS 50-28-2)

Estradiol (CAS 50-28-2)

See more	Hormone (25) Steroids (38) Endocrinology (337)

Description

Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. It is synthesized from testosterone primarily in the ovarian granulosa cells and placenta, but small amounts can be produced in the adrenal gland.^1,2 Plasma estradiol levels increase gradually between days 1-7 of the menstrual cycle followed by a sharp increase to a peak value of about 300 pg/ml on day 12, just prior to ovulation.^3,4

1 Vance, D.E. Cholesterol and related derivatives. 2nd ed. 725-748 (1988).

2 Miller, W.L., and Tyrrell, J.B. The adrenal cortex. 3rd edition 555-711 (1995).

3 Erickson, G.F. The ovary: Basic principles and concepts. A. Physiology. 3rd ed. 973-1015 (1995).

4 Munro, C.J., Stabenfeldt, G.H., Cragun, J.R., et al. Relationship of serum estradiol and progesterone concentrations to the excretion profiles of their major urinary metabolites as measured by enzyme immunoassay and radioimmunoassay. Clin Chem 37 838-844 (1991).

Synonyms	17β-Oestradiol 17β-Estradiol β-Estradiol
Formal Name	estra-1,3,5(10)-triene-3,17β-diol
CAS Number	50-28-2
Molecular Formula	C₁₈H₂₄O₂
Formula Weight	272.4
Formulation	A crystalline solid
Purity	≥98%
λ_max	203, 281 nm
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard Oc1ccc2c(CCC3C2CC[C@]2(C)[C@@H](O)CCC32)c1

Background Reading

Vance, D.E. Cholesterol and related derivatives. 2nd ed. 725-748 (1988).

Miller, W.L., and Tyrrell, J.B. The adrenal cortex. 3rd edition 555-711 (1995).

Munro, C.J., Stabenfeldt, G.H., Cragun, J.R., et al. Relationship of serum estradiol and progesterone concentrations to the excretion profiles of their major urinary metabolites as measured by enzyme immunoassay and radioimmunoassay. Clin Chem 37 838-844 (1991).

Erickson, G.F. The ovary: Basic principles and concepts. A. Physiology. 3rd ed. 973-1015 (1995).

Show all 4 Hide all but first 3

Size	Price	Quantity	Subtotal
500 mg	$9.00		$0.00
1 g	$17.00		$0.00
5 g	$72.00		$0.00
10 g	$126.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-05-25. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

2,3-bis (4-Hydroxyphenyl) Propionitrile

Prolactin (human) EIA Kit New

Propylpyrazole Triol

Testosterone EIA Kit

Tibolone

Show all 15 Hide all but first 3

Downloads

	Download Product Insert 110 Kb PDF
	Download Material Safety Data Sheet (MSDS) 16 Kb PDF
	Printer-friendly version of this page small PDF (usually less than 100 Kb)
	• US Letter paper 8½″ × 11″
	• A4 paper 21cm × 29.7cm
	Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Batch-specific Information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs	Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases	Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule	Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640