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10006350 HU-211
Dexanabinol
(CAS 112924-45-5)
HU-211 Workbook Links
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The endocannabinoids present a rich system of central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology that has stimulated research in many fields including memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation.1,2 HU-211 is a synthetic terpene-based cannabinoid devoid of CB1 and CB2 agonist activity, thus lacking the psychomotor responses characteristic of Δ9-THC. HU-211 does exhibit the neuroprotective, antioxidant properties of other related compounds like cannabidiol.3 HU-211 also has anti-inflammatory properties derived through inhibition of NF-κB and the resulting decreases in cytokines such as TNFα and IL-6.
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1
Pertwee, R.G. Pharmacology of cannabinoid receptor ligands. Current Medicinal Chemistry 6 635-664 (1999).
2
Martin, B.R., Mechoulam, R., Razdan, R.K. Discovery and characterization of endogenous cannabinoids. Life Sci 65 573-595 (1999).
3
Jüttler, E., Potrovita, I., Tarabin, V., et al. The cannabinoid dexanabinol is inhibitor of the nuclear factor-kappa B (NF-κB). Neuropharmacology 47 580-592 (2004).
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Purchase 10006350 HU-211
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Pricing updated 2010-03-17.
Prices are subject to change without notice.
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Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.
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