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dimethoxy Curcumin

Cayman Chemical Item Number 10009986

(CAS 160096-59-3)

dimethoxy Curcumin (CAS 160096-59-3)

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Formal Name 1,​7-​bis(3,​4-​dimethoxyphenyl)-​1,​6-​heptadiene-​3,​5-​dione
CAS Number 160096-59-3
Molecular Formula C23H24O6
Formula Weight 396.4
Formulation A crystalline solid
Purity ≥90%
λmax 418 nm
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES COC1=C(OC)​C=C(/C=C/C(CC(/C=C/C2=CC=C(OC)​C(OC)​=C2)​=O)​=O)​C=C1

Description

Naturally occurring phytochemicals such as turmeric (curcumin) have been found to inhibit the growth of tumor cells. dimethoxy Curcumiin is an analog of curcumin obtained by methylation of both free phenolic groups in the parent compound. A 30-fold increase in potency was observed in the growth suppression of HCT116 tumor cells following this modification. 1

1 Ohori, H., Yamakoshi, H., Tomizawa, M., et al. Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer. Mol Cancer Ther 5(10) 2563-2571 (2006).

Related Articles

Ohori, H., Yamakoshi, H., Tomizawa, M., et al. Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer. Mol Cancer Ther 5(10) 2563-2571 (2006).

dimethoxy Curcumin is available in the following screening library:

Pricing updated 2010-09-09. Prices are subject to change without notice.

Pricing is for North America only. Other customers should contact a distributor in their region.

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Warning This product is not for human or veterinary use.

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