dimethoxy Curcumin
Cayman Chemical Item Number 10009986
(CAS 160096-59-3)
dimethoxy Curcumin
(CAS 160096-59-3)
| Formal Name |
1,7-bis(3,4-dimethoxyphenyl)-1,6-heptadiene-3,5-dione |
| CAS Number |
160096-59-3 |
| Molecular Formula |
C23H24O6 |
| Formula Weight |
396.4 |
| Formulation |
A crystalline solid |
| Purity |
≥90% |
| λmax |
418 nm |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
Wet ice
in continental US; may vary elsewhere
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| SMILES |
COC1=C(OC)C=C(/C=C/C(CC(/C=C/C2=CC=C(OC)C(OC)=C2)=O)=O)C=C1
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Description
Naturally occurring phytochemicals such as turmeric (curcumin) have been found to inhibit the growth of tumor cells. dimethoxy Curcumiin is an analog of curcumin obtained by methylation of both free phenolic groups in the parent compound. A 30-fold increase in potency was observed in the growth suppression of HCT116 tumor cells following this modification. 1
1
Ohori, H., Yamakoshi, H., Tomizawa, M., et al. Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer. Mol Cancer Ther 5(10) 2563-2571 (2006).
Related Articles
Ohori, H., Yamakoshi, H., Tomizawa, M., et al. Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer. Mol Cancer Ther 5(10) 2563-2571 (2006).
dimethoxy Curcumin is available in the following screening
library:
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Pricing updated 2010-09-09.
Prices are subject to change without notice.
Pricing is for North America only. Other customers should contact a distributor in their region.
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