LY294002 is a selective phosphatidylinositol 3-kinase (PI3K) inhibitor with a 2.7-fold greater potency than quercetin. LY294002 inhibits purified PI3K with an IC50 of 1.4 µM.1
1
Vlahos, C.J., Matter, W.F., Hui, K.Y., et al. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem2695241-5248(1994).
Room temperature
in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
O=c1cc(oc2c(cccc12)c1ccccc1)N1CCOCC1
Background Reading
Vlahos, C.J., Matter, W.F., Hui, K.Y., et al. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem2695241-5248(1994).
LY294002 is available in the following screening
libraries: