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DETA NONOate

Cayman Chemical Item Number 82120

Diethylenetriamine NONOate (CAS 146724-94-9)

DETA NONOate (CAS 146724-94-9)

See more	NO Donors (26) Nitric Oxide (101)

Description

DETA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 20 hours and 56 hours at 37°C and 22-25°C, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound.^1,2

1 Hrabie, J.A., Klose, J.R., Wink, D.A., et al. New nitric oxide-releasing zwitterions derived from polyamines. J Org Chem 58 1472-1476 (1993).

2 Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms. Methods Enzymol 268 281-293 (1996).

Synonyms	Diethylenetriamine NONOate
Formal Name	(Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate
CAS Number	146724-94-9
Molecular Formula	C₄H₁₃N₅O₂
Formula Weight	163.2
Formulation	A crystalline solid
Purity	≥98%
λ_max	252 nm
ε	7
Stability	1 year
Storage	-80°C
Shipping	Dry ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard NCCN(CCN)N(O)N=O

Background Reading

Hrabie, J.A., Klose, J.R., Wink, D.A., et al. New nitric oxide-releasing zwitterions derived from polyamines. J Org Chem 58 1472-1476 (1993).

Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms. Methods Enzymol 268 281-293 (1996).

Size	Price	Quantity	Subtotal
10 mg	$17.00		$0.00
50 mg	$77.00		$0.00
100 mg	$136.00		$0.00
500 mg	$595.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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