An EGFR inhibitor
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AG-1557

Item No. 17989

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(3-iodophenyl)-6,7-dimethoxy-4-quinazolinamine
CAS Number
189290-58-2
Synonyms
  • Tyrphostin AG-1557
Molecular Formula
C16H14IN3O2
Formula Weight
407.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 1.5 mg/mlDMSO:PBS (pH 7.2)(1:8): 0.1 mg/mlEthanol: 0.5 mg/ml
λmax
221, 252, 345 nm
SMILES
IC1=CC(NC2=NC=NC3=CC(OC)=C(OC)C=C32)=CC=C1
InChi Code
InChI=1S/C16H14IN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
InChi Key
FGCLAQLIXMAIHT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $81

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    10 mg

    $152

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    25 mg

    $357

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    50 mg

    $633

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    Product Description

    AG-1557 is an inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase with a pIC50 value of 8.194.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Joshi, A., Gadhwal, M., and Joshi, U.J. Indentification of potential novel EGFR inhibitors using a combination of pharmacophore and docking methods. Int. J. Pharm. Pharmaceut. Sci. 7(6), (2015).