11β-Prostaglandin F Lipid Maps MS Standard
Item № 10007224
CAS № 38432-87-0
Purity >99%
product image
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
1 mg $137.00 $0.00
5 mg $617.00 $0.00
10 mg $1,096.00 $0.00

Pricing updated 2015-09-05. Prices are subject to change without notice.

Bulk Inquiry Form

X

Enter number, size, and select unit. Example: 2 x 500 mg

Please indicate any analytical testing requirements, special handling, packaging, or delivery requirements.

Description
Synonyms
  • 11-epi PGF
  • 11β-PGF

11β-Prostaglandin F (11β-PGF) is the primary plasma metabolite of PGD2 in vivo.1 Normal human urinary excretion of 11β-PGF is about 54 ng/mmol creatinine, which is increased nearly 3-fold upon allergen-induced bronchoconstriction in asthmatics.2 It is equipotent to PGF in inducing human bronchial smooth muscle contractions and inhibition of adipose differentiation.3,4 11β-PGF inhibits ADP or thrombin-induced human platelet aggregation at concentrations of 0.14-2.8 µM.5

Download Product Insert Download Safety Data Sheet (SDS)

Related Products

Show all 4 Hide all but first 3

View Related Product Categories
Technical Information
Formal Name 9α,​11β,​15S-​trihydroxy-​prosta-​5Z,​13E-​dien-​1-​oic acid
CAS Number 38432-87-0
Synonyms
  • 11-epi PGF
  • 11β-PGF
Molecular Formula C20H34O5
Formula Weight 354.5
Purity >99%
Formulation A crystalline solid
SMILES O[C@@H]​1[C@H]​(/C=C/[C@@H]​(O)​CCCCC)​[C@@H]​(C/C=C\CCCC(O)​=O)​[C@@H]​(O)​C1
InChI Code ​1S/C20H34O5/c1-2-3-6-9-15(21)​12-13-17-16(18(22)​14-19(17)​23)​10-7-4-5-8-11-20(24)​25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)​/b7-4-,13-12+/t15-,16+,17+,18-,19-/m0/s1
InChI Key PXGPLTODNUVGFL-ZWAKLXPCSA-N

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years
Product Downloads & Resources
Product Downloads

Download Product Insert 99 Kb PDF

Download Safety Data Sheet (SDS) 28 Kb PDF

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Separate multiple batch numbers with commas

Inserts
QC Sheets
Certificates of Analysis
GCMS Data
References & Background Reading
Product Description References

1. Liston, T.E., and Roberts, L.J. Transformation of prostaglandin D2 to 9α,11β-(15S)-trihydroxy-prosta-(5Z,13E)-dien-1-oic acid (9α,11β-prostaglandin F2): A unique biologically active prostaglandin produced enzymatically in vivo in humans. Proc Natl Acad Sci USA 82 6030-6034 (1985).

2. O'Sullivan, S., Dahlén, B., Dahlén, S., et al. Increased urinary excretion of the prostaglandin D2 metabolite 9α,11β-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction. J Allergy Clin Immunol 98 421-432 (1996).

3. Coleman, R.A., and Sheldrick, R.L.G. Prostanoid-induced contraction of human bronchial smooth muscle is mediated by TP-receptors. Br J Pharmacol 96 688-692 (1989).

4. Lepak, N.M., and Serrero, G. Inhibition of adipose differentiation by 9α, 11β-prostaglandins F. Prostaglandins 46 511-517 (1993).

5. Pugliese, G., Spokas, E.G., Marcinkiewicz, E., et al. Hepatic transformation of prostaglandin D2 to a new prostanoid, 9α,11β-prostaglandin F2, that inhibits platelet aggregation and constricts blood vessels. J Biol Chem 260 14621-14625 (1985).

Technical Support
Contact Us
  • To streamline the process attach the appropriate questionnaire to your inquiry.

  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Contract Research Services

We offer you the deep and diverse knowledge of more than 100 in-house scientists and the expertise that comes from more than three decades of designing and developing the tools to advance biomedical research.

Cayman is know as a partner to scientists worldwide, responding to your needs with services in:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

JOIN OUR SOCIAL NETWORK!

Please wait...