A chemical source of superoxide anion in aqueous solution
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

SOTS-1 (technical grade)

Item No. 10009642

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4,4’-[azobis(oxymethylene]bis-benzoic acid
CAS Number
223507-96-8
Synonyms
  • Superoxide Thermal Source
  • Di-(4-Carboxybenzyl)Hyponitrite
Molecular Formula
C16H14N2O6
Formula Weight
330.3
Purity
≥80%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 2 mg/mlDMF:PBS(pH 7.2)(1:2): 0.3 mg/mlDMSO: 10 mg/ml
SMILES
O=C(O)C1=CC=C(CON=NOCC2=CC=C(C(O)=O)C=C2)C=C1
InChi Code
InChI=1S/C16H14N2O6/c19-15(20)13-5-1-11(2-6-13)9-23-17-18-24-10-12-3-7-14(8-4-12)16(21)22/h1-8H,9-10H2,(H,19,20)(H,21,22)
InChi Key
KNKCXZHPOIMNJH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 µg

    $36

    Add

    1 mg

    $49

    Add

    5 mg

    $203

    Add

    10 mg

    $336

    Add
    Product Description

    SOTS-1 is an azo-compound that can be thermally decomposed in aqueous solution to generate superoxide radical anion at a constant, controlled rate. More specifically, SOTS-1 thermally decomposes to form an intermediate that reacts with oxygen at the diffusion-controlled limit to generate superoxide radical anion. The decay of SOTS-1 into the intermediate follows first order kinetics, and exhibits a half-life of 4900 seconds at physiological pH and temperature.1,2 This allows for study of the effect of superoxide on biologically relevant systems in a controlled environment that closely mimics conditions in vivo.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Konya, K.G., Paul, T., Lin, S., et al. Laser flash photolysis studies on the first superoxide thermal source. First direct measurements of the rates of solvent-assisted 1,2-hydrogen atom shifts and a proposed new mechanism for this unusual rearrangement. J. Am. Chem. Soc. 122(31), 7518-7527 (2000).

    2. Ingold, K.U., Paul, T., Young, M.J., et al. Invention of the first azo compound to serve as a superoxide thermal source under physiological conditions: Concept, synthesis, and chemical properties. J. Am. Chem. Soc. 119(50), 12364-12365 (1997).