A 9,11-diketo analog of PGE1 or PGD1
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Prostaglandin K1

Item No. 18800

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9,11-dioxo-15S-hydroxy-prost-13E-en-1-oic acid
CAS Number
69413-73-6
Synonyms
  • PGK1
Molecular Formula
C20H32O5
Formula Weight
352.5
Purity
≥95%
Formulation
A 1 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: >100 mg/ml (from PGD2)DMSO: >50 mg/ml (from PGD2)Ethanol: >75 mg/ml (from PGD2)PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-d12,
λmax
245 nm
SMILES
O=C(C1)[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)C1=O
InChi Code
InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,21H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+/m0/s1
InChi Key
KJWZYMMLVHIVSU-IYCNHOCDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 µg

    $53

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    500 µg

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    1 mg

    $423

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    5 mg

    $1,716

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    Product Description

    Prostaglandin K1 (PGK1) is a 9,11-diketo analog of PGE1 (Item No. 13010) or PGD1 (Item No. 12000). It is a PGE2 receptor subtype EP1 agonist that has 387-fold reduced potency compared to PGE2 (Item No. 14010).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ungrin, M.D., Carrière, M.C., Denis, D., et al. Key structural features of prostaglandin E2 and prostanoid analogs involved in binding and activation of the human EP1 prostanoid receptor. Mol. Pharmacol. 59(6), 1446-1456 (2001).

    Product Citations

    Wu, Z., Xiao, H., Rao, D., et al. Analytical strategy for oxylipin annotation by combining chemical derivatization-based retention index algorithm and feature tandem mass spectrometric fragmentation as a biomarker discovery tool. Anal. Chem. 95(43), 15933-15942 (2023).