Literature & Media

Immunoaffinity Mass Spectrometry for Leukotriene Analysis in Brain

Application notes

Key Information

  • Leukotrienes (LTs) are acute inflammatory mediators that are extremely difficult to isolate and quantify in biological tissues.
  • Isolation and quantification of LTs in brain tissue is explored using immunoaffinity capture LC-MS/MS (IA-MS) vs. SPE-MS.
  • IA-MS outperformed SPE-MS for LTs allowing for lower level quantitation of these analytes using a simplified, reproducible workflow.
To cite this application note: Kennedy, P.D., Dorow, S., Bickel, J., et al. Immunoaffinity mass spectrometry for leukotriene analysis in brain. Application Note, Cayman Chemical (2017).
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Immunoaffinity Mass Spectrometry for Leukotriene Analysis in Brain
Cayman ChemicalCayman ChemicalCayman Chemical

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