Literature & Media

Creating Custom Cannabis CRM Mixtures: Forty-seven Phytocannabinoids, One HPLC Method

Application notes

The development of custom phytocannabinoid certified reference material (CRM) mixtures requires a robust method to resolve coeluting components. This study presents the development and validation of a method addressing the separation of 47 phytocannabinoid compounds.

Highlights:

  • Chromatography was run on 47 phytocannabinoid compounds (12 acid and 35 neutral).
  • Co-eluting neutral compounds were identified and segregated for the acceptable validation of an HPLC method. 
  • This method supports Cayman’s quick turn production of custom phytocannabinoid CRMs.

To cite this application note: Franckowski, R., Gregerson, M., Calati, K., et al. Creating Custom Cannabis CRM Mixtures: Forty-seven Phytocannabinoids, One HPLC Method. Application Note, Cayman Chemical (2025).

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<p>Creating Custom <em>Cannabis </em>CRM Mixtures&#58; Forty-seven Phytocannabinoids, One HPLC Method<br></p>
Cayman ChemicalCayman ChemicalCayman Chemical

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