Drug metabolites play a major role in identifying, confirming, and quantifying drugs of abuse. They are often the only remaining evidence of a rapidly metabolized drug, and their predictive fragmentation patterns provide much-needed clues for identifying unknowns. Cayman Chemical offers Certified Reference Materials (CRMs) for many of the major metabolites of opioids, benzodiazepines, stimulants, cannabinoids, and more. Our CRMs meet ISO/IEC 17025 and ISO 17034 standards and are sold as quantitative solutions in sealed ampules.