Literature & Media

The Roles of ENPP1 Activity and 2’3’-cGAMP Degradation in Ovarian Cancer Cell Lines

Scientific posters

Recent studies have shown that ENPP1 may play a role in cancer cell proliferation, migration, and invasion in ovarian and other types of cancer. In this study, we investigated whether ENPP1 activity and its hydrolysis of 2'3'-cAMP correlate with ENPP1 expression levels in ovarian cancer cell lines. We also tested whether published ENPP1 inhibitors can inhibit ENPP1 activity in cell-free assays and cell culture model, and if inhibition of ENPP1 affects the viabilities of ovarian cancer cell lines. 

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To cite this poster: Briggs, H.L., Collins, M.L, Clements, L., et al. The Roles of ENPP1 Activity and 2’3’-cGAMP Degradation in Ovarian Cancer Cell Lines. Poster presented at: American Society for Biochemistry and Molecular Biology Annual Meeting; March 25-28; Seattle, WA.
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The Roles of ENPP1 Activity and 2’3’-cGAMP Degradation in Ovarian Cancer Cell Lines
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