Literature & Media

Lipidomics Analysis Reveals Changes in the Regulation of Lipid Metabolism in a Surgical Bone Defect Model

Scientific posters

Lipids play critical roles in the physiology of biological systems. Comprehensive analysis of lipid profiles is being increasingly used to detect biomarkers and to generate hypotheses to help characterize potential mechanisms of disease progression that may offer novel preventive or therapeutic approaches. Advances in liquid chromatography and mass spectrometry instrumentation, and in specialized software, enable identification and relative quantitation of a wide variety of lipid species, providing powerful tools for the investigation of lipid profile changes over time. 

The present study illustrates those advances by identifying large numbers of lipid molecular species in a variety of tissues collected at different times post-surgery from a femoral defect model in rats treated with a prostaglandin receptor agonist.

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To cite this poster: Palagama, D.S.W., Kwiatkowski, M.J., Rzeczycki, P.M., et al. Lipidomics Analysis Reveals Changes in the Regulation of Lipid Metabolism in a Surgical Bone Defect Model. Poster presented at: 71st ASMS Conference on Mass Spectrometry and Allied Topics 3; June 4-8, 2023; Houston, TX.
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Lipidomics Analysis Reveals Changes in the Regulation of Lipid Metabolism in a Surgical Bone Defect Model<br>
Cayman ChemicalCayman ChemicalCayman Chemical

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