Literature & Media

Metabolic Profiling of the Semi-synthetic Tetrahydrocannabinols (THCs), Δ10-THC and Δ6a,10a-THC, Using Human Liver Microsomes and LC/MS

Webinars

The pharmacology of several naturally occurring phytocannabinoid constituents of Cannabis sativa L., such as Δ9-THC, has previously been studied and well-documented in the scientific literature. However, since the deregulation of hemp in the 2018 USDA Farm Bill, new semi-synthetic structurally related isomers, analogs, and homologs have emerged, presenting new chemical entities with unknown metabolic profiles.

Listen as Nathan Layle, a synthetic organic chemist at Cayman Chemical, discusses the LC/MS-based identification of putative in vitro metabolites of the semi-synthetic tetrahydrocannabinols Δ10-THC and Δ6a,10a-THC.

Presented as part of the 77th Annual Scientific Conference of the American Academy of Forensic Sciences.

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Cayman ChemicalCayman ChemicalCayman Chemical

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