Literature & Media

​mRNA Delivery to Activated Primary Human T Cells Using C14-4 Lipid Nanoparticles

Application notes

Key Features

  • Primary immune cells, especially T cells, are challenging to transfect due to their natural resistance to foreign genetic material.
  • Lipid nanoparticles (LNPs) offer improved efficiency with reduced cytotoxicity compared with traditional transfection methods.
  • This workflow can be used with LNPs for the delivery of mRNA to achieve optimal protein expression in activated primary human T cells.
To cite this application note: Nyayapathy, S. and Rumble, J. mRNA delivery to activated primary human T cells using C14-4 lipid nanoparticles. Application Note, Cayman Chemical (2024). 
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<p>​mRNA Delivery to Activated Primary Human T Cells Using C14-4 Lipid Nanoparticles<br></p>
Cayman ChemicalCayman ChemicalCayman Chemical

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