Literature & Media

Evaluation of Quantification Capabilities of Untargeted Lipidomics Approaches

Application notes


​We evaluated the accuracy of lipid quantitation in human plasma by LC-MS using single-point or multipoint calibration curves with authentic or surrogate standards.

Highlights: 

  • Both methods identified hundreds of lipids with precision and accuracy.
  • Multipoint calibration curves outperformed single-point calibration curves.
  • The proper selection of standards is critical for quantitation accuracy.
To cite this application note: Kennedy, P.D., Palagama, D.S.W., Kwiatkowski, M.J., et al. Evaluation of the quantification capabilities of untargeted lipidomics approaches. Application Note, Cayman Chemical Company (2025).
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<p>Evaluation of&#160;Quantification Capabilities of Untargeted Lipidomics Approaches<br></p>
Cayman ChemicalCayman ChemicalCayman Chemical

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