Oxylipins, produced by the oxidation of polyunsaturated fatty acids (PUFAs), are lipid mediators involved in a variety of biological mechanisms of health and disease. Octadecanoids are 18-carbon oxylipins derived from linoleic or linolenic acids, and they are increasingly recognized as having important effects in biological responses. This study shows the synthesis and characterization of twelve new standards for epoxy-octadecadienoic acids (EpODEs) and dihydroxy-octadecadienoic acids (DiHODEs) derived from α-linolenic acid (ALA) and γ-linolenic acid (GLA), which expand the availability of biochemical tools to further investigate the biological roles of octadecanoids. 

Do you have a question or comment for the presenter? Let us know.

To cite this poster: DeLoy, S., Dittmer, J., LaGory, D., et al. Synthesis and Characterization of New Octadecanoid Standards. Poster presented at: 5^th EpiLididNET Action Meeting; May 13-15, 2024. Dresden, Germany.