Citrulline is a non-proteinogenic amino acid that is produced by deimination of arginine through the post-translational modification known as citrullination. Protein citrullination plays a vital role in many physiological and pathological processes including autoimmunity, cancer, and neurodegenerative disorders. Here we validate and characterize the anti-citrulline antibodies produced by Cayman through Immunofluorescence, ELISA, and Surface Plasmon Resonance.

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To cite this poster: Muzzarelli, K., Bickel, J., Norris, C., et al. Validation and Characterization of Anti-Citrulline Antibodies and Citrullinated Proteins. Poster presented at: 21^st Annual Drug Discovery Chemistry Conference; April 13-16, 2026; San Diego, CA.