A cytochrome c-dependent inducer of apoptosis
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CAY10443

Item No. 10004177

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
[(3,4-dichlorophenyl)methyl]-carbamic acid, (1S)-2,3-dihydro-1H-inden-1-yl ester
CAS Number
582314-48-5
Synonyms
  • (S)-Indan-1-yl 3,4-dichlorobenzylcarbamate
Molecular Formula
C17H15Cl2NO2
Formula Weight
336.2
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 25 mg/mlDMSO:PBS (pH 7.2)(1:2:): .25 mg/mlEthanol: 5 mg/ml
SMILES
O=C(NCc1ccc(Cl)c(Cl)c1)O[C@H]1CCc2ccccc12
InChi Code
InChI=1S/C17H15Cl2NO2/c18-14-7-5-11(9-15(14)19)10-20-17(21)22-16-8-6-12-3-1-2-4-13(12)16/h1-5,7,9,16H,6,8,10H2,(H,20,21)/t16-/m0/s1
InChi Key
CKERQCMQSBFFKX-INIZCTEOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

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    10 mg

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    25 mg

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    Product Description

    CAY10443 is one such molecule. In a cell free, multi-component assay, it activated caspase-3 with an EC50 of 5 µM.1 These apoptotic activators represent therapeutic lead compounds for the development of antitumor drugs.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nguyen, J.T., and Wells, J.A. Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc. Natl. Acad. Sci. USA 100(13), 7533-7538 (2003).