For immunochemical detection of PCNA
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PCNA Monoclonal Antibody (Clone IPO-38)

Item No. 10004805

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Nuclear Antigen of Proliferating Cells
  • Proliferating Cell Nuclear Antigen
Clone Designation
IPO-38
Formulation (Request formulation change)
100 µg of affinity-purified monoclonal antibody
Storage Buffer
200 µl PBS, pH 7.2, with 0.02% sodium azide
Host
Mouse
Isotype
IgM
Applications
FC, ICC, IHC (frozen and paraffin-embedded sections), WB
Species Reactivity
(+) Multiple species PCNA (species- and tissue-unspecific)
Origin
Animal/Mouse
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    1 ea (100 µg)

    $347

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    Product Description

    The proliferating cell nuclear antigen (PCNA) becomes detectable in the G1 phase of the cell cycle and reaches a maximum level of expression during mitosis. PCNA is highly conserved across species and is a critical part of the DNA polymerase δ holoenzyme.1,2,3 The level of PCNA expression depends on the proliferative potential of the cell examined. Caymanl’s PCNA Monoclonal Antibody can be used for analysis of PCNA by Western blot, flow cytometry, immunocytochemistry, and immunohistochemistry (frozen and paraffin-embedded tissue) on samples from multiple species. This monoclonal antibody stains proliferating cells in a wide range of normal tissues, as well as in tissues undergoing pathological processes and after mitogenic and allogeneic stimulations.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tan, C.K., Castillo, C., So, A.G., et al. An auxiliary protein for DNA polymerase-δ from fetal calf thymus. The Journal of Biological Chemisty 261(26), 12310-12316 (1986).

    2. Fukuda, K., Morioka, H., Imajou, S., et al. Structure-function relationship of the eukaryotic DNA replication factor, proliferating cell nuclear antigen. The Journal of Biological Chemisty 270(38), 22527-22534 (1995).

    3. Travali, S., Ku, D.H., Rizzo, M.G., et al. Structure of the human gene for the proliferating cell nuclear antigen. The Journal of Biological Chemisty 264(13), 7466-7472 (1989).