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Item No. 10004837
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CD27 is a type II homodimeric transmembrane glycoprotein (Mr = 55 kDa) and a member of the nerve growth factor/tumor necrosis receptor superfamily.1,2 The antigen was identified on medullar thymocytes, mature T lymphocytes (CD45RA+CD45RO-
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1. CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein. Proc. Natl. Acad. Sci. USA 94(12), 6346-6351 (1997).
2. The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family. J. Immunol. 147, 3165-3169 (1991).