Less active isomer of (+)-Cloprostenol
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(+)-5-trans Cloprostenol

Item No. 10004970

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
[1R-[1α(E),2β(1E,3R*),3α,5α]]-7-[2-[4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid
CAS Number
57968-81-7
Synonyms
  • D-Cloprostenol
  • (+)-5,6-trans Cloprostenol
  • (+)-5-trans-16-m-chlorophenoxy tetranor PGF2α
  • (+)-5-trans-16-m-chlorophenoxy tetranor Prostaglandin F2α
Molecular Formula
C22H29ClO6
Formula Weight
424.9
Purity
≥95%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: >100 mg/mlDMSO: >100 mg/mlEthanol: >100 mg/mlPBS (pH 7.2): >16 mg/ml
SMILES
OC1[C@H](C/C=C/CCCC(O)=O)[C@@H](/C=C/[C@@H](O)COC2=CC(Cl)=CC=C2)C(O)C1
InChi Code
InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1+,11-10+/t16-,18-,19-,20+,21-/m1/s1
InChi Key
VJGGHXVGBSZVMZ-BDFMIYKPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $94

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    5 mg

    $366

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    10 mg

    $684

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    25 mg

    $1,477

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    Product Description

    Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses. (+)-5-trans Cloprostenol is a minor impurity produced in the synthesis of (+)-cloprostenol. The (+)-5-trans isomer is 20-fold less active than the 5-cis form in terminating pregnancy in the hamster.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bowler, J., Brown, E.D., Crossley, N.S., et al. Double bond isomers of cloprostenol. Prostaglandins 17(6), 789-800 (1979).