An arachidonoyl amino acid
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Labeled Version(s)
26323N-Arachidonoyl Taurine-d4
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N-Arachidonoyl Taurine

Item No. 10005537

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[(1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl)amino]-ethane sulfonic acid
CAS Number
119959-65-8
Molecular Formula
C22H37NO4S
Formula Weight
411.6
Purity
≥98%
Formulation (Request formulation change)
A 5 mg/ml in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 20 mg/mlPBS (pH 7.2): 1.5 mg/ml
SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(N(CCS(=O)(O)=O)[H])=O
InChi Code
InChI=1S/C22H37NO4S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(24)23-20-21-28(25,26)27/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,23,24)(H,25,26,27)/b7-6-,10-9-,13-12-,16-15-
InChi Key
YUNYSWCRLRYOPO-DOFZRALJSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $61

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    1 mg

    $109

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    5 mg

    $455

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    10 mg

    $726

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    Product Description

    N-Arachidonoyl taurine is an arachidonoyl amino acid.1 It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages.2 N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 µM, respectively).1 It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 µM and increases insulin secretion from 832/13 INS-1 pancreatic β-cells.3 The levels of N-arachidonoyl taurine are changed in mouse brain following administration of Δ9-tetrahydrocannabinol (Δ9-THC).4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
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