A fully saturated anandamide analog
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Arachidoyl Ethanolamide

Item No. 10005765

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2-hydroxyethyl)-eicosanamide
CAS Number
94421-69-9
Synonyms
  • N-Arachidoylethanolamine
Molecular Formula
C22H45NO2
Formula Weight
355.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlEthanol: 2.5 mg/mlPBS (pH 7.2): 0.15 mg/ml
SMILES
CCCCCCCCCCCCCCCCCCCC(=O)NCCO
InChi Code
InChI=1S/C22H45NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h24H,2-21H2,1H3,(H,23,25)
InChi Key
AUJVQJHODMISJP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $44

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    10 mg

    $80

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    25 mg

    $187

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    50 mg

    $351

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    Product Description

    Arachidoyl ethanolamide is one of the saturated fatty acyl ethanolamides devoid of classical (CB1/CB2) activity. Arachidoyl ethanolamide does not bind to the murine CB1 receptor and does not compete with anandamide as a substrate for the endocannabinoid hydrolytic enzyme fatty acid amide hydrolase.1,2 Non-CB receptor-mediated pharmacology of the saturated ethanolamides is still being elucidated.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sheskin, T., Hanus, L., Slager, J., et al. Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor. J. Med. Chem. 40(5), 659-667 (1997).

    2. Desarnaud, F., Cadas, H., and Piomelli, D. Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization. The Journal of Biological Chemisty 270(11), 6030-6035 (1995).

    3. Smart, D., Jonsson, K.O., Vandevoorde, S., et al. “Entourage” effects of N-acyl ethanolamines at human vanilloid receptors. Comparison of effects upon anandamide-induced vanilloid receptor activation and upon anandamide metabolism. Br. J. Pharmacol. 136, 452-458 (2002).