A derivative of resveratrol
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Product Type

Biochemicals

Research Area

PDM 11

Item No. 10006341

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(E)-5-[2-(4-chlorophenyl)ethenyl]-1,3-dimethoxyphenyl
CAS Number
1032508-03-4
Molecular Formula
C16H15ClO2
Formula Weight
274.7
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS (pH 7.2)(1:2): .3 mg/mlDMSO: 20 mg/mlEthanol: 2 mg/ml
λmax
213, 303 nm
SMILES
ClC(C=C1)=CC=C1/C=C/C2=CC(OC)=CC(OC)=C2
InChi Code
InChI=1S/C16H15ClO2/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11H,1-2H3/b4-3+
InChi Key
VPHHOTWBLKKBBT-ONEGZZNKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    10 mg

    $29

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    25 mg

    $68

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    50 mg

    $123

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    100 mg

    $215

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    Product Description

    PDM 11 is a derivative of the antioxidant trans-resveratrol that is inactive in vitro in assays of resveratrol activity.1 It does not activate quinone reductase 1, inhibit quinone reductase 2, or affect nitric oxide production or quenching of free radicals. It does not interact with estrogen receptors or affect the activity of COX-1 and COX-2. PDM 11 does not affect proliferation of K562, HT-29, and HepG2 cells.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kondratyuk, T.P., Park, E.J., Marler, L.E., et al. Resveratrol derivatives as promising chemopreventive agents with improved potency and selectivity. Mol. Nutr. Food Res. 55(8), 1249-1265 (2011).

    2. Chen, Y., Hu, F., Gao, Y., et al. Design, synthesis, and evaluation of methoxylated resveratrol derivatives as potential antitumor agents. Res. Chem. Intermed. 41(5), 2725–2738 (2015).