An inhibitor of ACAT
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

CAY10486

Item No. 10006452

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-L-phenylalanine, methyl ester
CAS Number
615264-52-3
Synonyms
  • 4-hydroxy Cinnamic Acid (L-Phenylalanine methyl ester) amide
Molecular Formula
C19H19NO4
Formula Weight
325.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2)(1:5): 0.5 mg/mlEthanol: 20 mg/ml
λmax
210, 226, 311 nm
SMILES
O=C(N[C@@H](CC1=CC=CC=C1)C(OC)=O)/C=C/C2=CC=C(O)C=C2
InChi Code
InChI=1S/C19H19NO4/c1-24-19(23)17(13-15-5-3-2-4-6-15)20-18(22)12-9-14-7-10-16(21)11-8-14/h2-12,17,21H,13H2,1H3,(H,20,22)/b12-9+
InChi Key
ATJBWQGWPYQIAR-FMIVXFBMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $33

    Add

    10 mg

    $63

    Add

    25 mg

    $148

    Add

    50 mg

    $246

    Add
    Product Description

    CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 µM.1 It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 µM.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lee, S., Han, J.M., Kim, H., et al. Synthesis of cinnamic acid derivatives and their inhibitory effects on LDL-oxidation, acyl-CoA: Cholesterol acyltransferase-1 and -2 activity, and decrease of HDL-particle size. Bioorg. Med. Chem. Lett. 14(18), 4677-4681 (2004).