A cathepsin K inhibitor
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

2-cyano-Pyrimidine

Item No. 10007121

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-pyrimidinecarbonitrile
CAS Number
14080-23-0
Molecular Formula
C5H3N3
Formula Weight
105.1
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 3 mg/ml
λmax
213, 254 nm
SMILES
N#CC1=NC=CC=N1
InChi Code
InChI=1S/C5H3N3/c6-4-5-7-2-1-3-8-5/h1-3H
InChi Key
IIHQNAXFIODVDU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 mg

    $13

    Add

    1 g

    $21

    Add

    5 g

    $86

    Add

    10 g

    $152

    Add
    Product Description

    2-cyano-Pyrimidine is a cathepsin K inhibitor whose basic structure and derivatives are being studied for the treatment of osteoporosis. 2-cyano-Pyrimidine has an IC50 value of 170 nM for inhibition of cathepsin K.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Carroll, J., Smith, N., and Babson, A.L. A colorimetric serum glucose determination using hexokinase and glucose-6-phosphate dehydrogenase. Biochem. Med. 4(2), 171-180 (1970).