For immunochemical detection of GPR35
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Product Categories

Product Type

Antibodies
Primary Antibodies
Polyclonal Antibodies

Research Area

Application

Immunohistochemistry
Western Blot

GPR35 Polyclonal Antibody

Item No. 10007660

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • G Protein-Coupled Receptor 35
  • KYNA Receptor
Immunogen
Synthetic peptide from the C-terminal region of human GPR35
Formulation (Request formulation change)
500 µl of peptide affinity-purified polyclonal antibody
Storage Buffer
PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide
Host
Rabbit
Applications
IHC (paraffin-embedded tissue) and WB
Species Reactivity
(+) Human(+) Mouse(+) Porcine
UniProt Accession №
Q9HC97
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    1 ea (500 µl)

    $347

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    Product Description

    Many G protein-coupled receptor 35 (GPR35) ligands have recently been identified including kynurenic acid (Item No. 16762) and zaprinast (Item No. 110010421).1,2 Multiple isoforms of this receptor have been reported and GPR35 mRNAs were detected in several tissues including intestine, lymphocytes, skeletal muscle, pancreatic β cells, and tumor cell lines.1,3 Cayman’s GPR35 Polyclonal Antibody has been used successfully to detect this receptor in human and mouse intestine samples as well as in human, mouse, and porcine lymphocytes at 30 kDa on immunoblot.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wang, J., Simonavicius, N., Wu, X., et al. Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. The Journal of Biological Chemisty 281(31), 22021-22028 (2006).

    2. Taniguchi, Y., Tonai-Kachi, H., and Shinjo, K. Zaprinast, a well-known cyclic guanosine monophosphate-specific phosphodiesterase inhibitor, is an agonist for GPR35. FEBS Lett. 580(21), 5003-5008 (2006).

    3. Okumura, S.i., Baba, H., Kumada, T., et al. Cloning of a G-protein-coupled receptor that shows an activity to transform NIH3T3 cells and is expressed in gastric cancer cells. Cancer Sci. 95(2), 131-135 (2004).