Fluorescently tagged dihydro-sphingosine
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C6 NBD dihydro Ceramide (d18:0/6:0)

Item No. 10007957

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-hexanamide
CAS Number
114301-97-2
Synonyms
  • NBD Cer(d18:0/6:0)
  • NBD Ceramide (d18:0/6:0)
  • N-C6-NBD-D-erythro-dihydro-Sphingosine
Molecular Formula
C30H51N5O6
Formula Weight
577.8
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlDMSO:PBS (pH 7.2) (1:2): 0.3 mg/mlEthanol: 0.5 mg/ml
λmax
229, 265, 332, 464 nm
SMILES
OC[C@H](NC(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C12)=O)[C@@H](CCCCCCCCCCCCCCC)O
InChi Code
InChI=1S/C30H51N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h20-21,25,27,31,36-37H,2-19,22-23H2,1H3,(H,32,38)/t25-,27+/m0/s1
InChi Key
GEZLBJRDZRUTOE-AHKZPQOWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $196

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    5 mg

    $873

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    10 mg

    $1,548

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    Product Description

    C6 NBD dihydro ceramide (d18:0/6:0) is structurally identical to C6 NBD ceramide, except it contains a saturated bond in the C-4/C-5 position of the sphingosine backbone.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Pitman, M., Lewis, A.C., Davies, L.T., et al. The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism. Sci. Rep. 12(1), 454 (2022).

    McNaughton, M., Pitman, M., Pitson, S.M., et al. Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells. Oncotarget 7(13), 16663-16675 (2016).