Isomer of bimatoprost
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15(R)-17-phenyl trinor Prostaglandin F2α ethyl amide

Item No. 10008127

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-ethyl-9α,11α,15R-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide
CAS Number
1163135-92-9
Synonyms
  • 15(R)-Bimatoprost
  • 15(R)-17-phenyl trinor PGF2α ethyl amide
Molecular Formula
C25H37NO4
Formula Weight
415.6
Purity
≥98%
Formulation (Request formulation change)
A 5 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
Acetonitrile: 3 mg/mlDMF: 25 mg/mlDMSO: 25 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 0.3 mg/ml
SMILES
CCNC(=O)CCC/C=C\CC1C(O)CC(O)[C@@H]1\C=C\[C@H](O)CCc1ccccc1
InChi Code
InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21-,22-,23+,24-/m1/s1
InChi Key
AQOKCDNYWBIDND-ZPFRTTICSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $82

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    1 mg

    $154

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    5 mg

    $642

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    10 mg

    $1,042

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    Product Description

    17-phenyl trinor PG2α ethyl amide is an analog of PG2α that is used topically for the treatment of glaucoma and ocular hypertension. 15(R)-17-phenyl trinor PG2α ethyl amide is an isomer of 17-phenyl trinor PG2α ethyl amide, characterized by an inverted (β) hydroxyl group at C-15. While this isomer has not been characterized, the comparable inversion of 15-hydroxyl groups, from (S) to (R), on other PGF2α analogs typically decreases, but does not eliminate, activity.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Resul, B., Stjernschantz, J., No, K., et al. Phenyl-substituted prostaglandins: Potent and selective antiglaucoma agents. J. Med. Chem. 36(2), 243-248 (1993).