A more lipid-soluble, cell-permeable prodrug form of PGD2
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Active Metabolite(s)
12010Prostaglandin D2
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Prostaglandin D2 methyl ester

Item No. 10008385

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9α,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid, methyl ester
CAS Number
49852-81-5
Synonyms
  • PGD2 methyl ester
Molecular Formula
C21H34O5
Formula Weight
366.5
Purity
≥97%
Formulation (Request formulation change)
A 5 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/mlPBS (pH 7.2): 1 mg/ml
SMILES
CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1C/C=C\CCCC(=O)OC
InChi Code
InChI=1S/C21H34O5/c1-3-4-7-10-16(22)13-14-18-17(19(23)15-20(18)24)11-8-5-6-9-12-21(25)26-2/h5,8,13-14,16-19,22-23H,3-4,6-7,9-12,15H2,1-2H3/b8-5-,14-13+/t16-,17+,18+,19-/m0/s1
InChi Key
WNBMQMMGBBWUOZ-BYNKDMOPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $48

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    1 mg

    $90

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    5 mg

    $366

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    Product Description

    Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2.1 It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Suzuki, F., Hayashi, H., Ito, S., et al. Methyl ester of prostaglandin D2 as a delivery system of prostaglandin D2 into brain. Biochim. Biophys. Acta 917, 224-230 (1987).

    2. Hirai, H., Abe, H., Tanaka, K., et al. Gene structure and functional properties of mouse CRTH2, a prostaglandin D2 receptor. Biochem. Biophys. Res. Commun. 307, 797-802 (2003).