A synthetic phosphatidylinostiol for signal transduction research
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PtdIns-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt)

Item No. 10008398

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(1,2R-dihexadecanoylphosphatidyl)inositol-3,5-bisphosphate, trisodium salt
Synonyms
  • DPPI-3,5-P2
  • Phosphatidylinositol-3,5-diphosphate C-16
  • PIP2[3',5'](16:0/16:0)
  • PI(3,5)P2 (16:0/16:0)
Molecular Formula
C41H78O19P3 • 3Na
Formula Weight
1036.9
Purity
≥98%
Formulation (Request formulation change)
A lyophilized powder
Solubility(Learn about Variance in Solubility)
50 mM HEPES*: 8 mg/mlCHCl3:CH3OH:H2O (3:2:1): 10 mg/mlPBS (pH 7.2): 1 mg/ml (opaque solution)
SMILES
O[C@@H]1[C@H](OP([O-])(O)=O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@@H]1OP([O-])(OC[C@H](OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O.[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C41H81O19P3.3Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)55-31-33(57-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-56-63(53,54)60-41-37(45)39(58-61(47,48)49)36(44)40(38(41)46)59-62(50,51)52;;;/h33,36-41,44-46H,3-32H2,1-2H3,(H,53,54
InChi Key
NBKRWHZNPNTETQ-PBBZQLKASA-K
Side Chain Carbon Sum
32:0
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    100 µg

    $70

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    500 µg

    $303

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    1 mg

    $535

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    Product Description

    Phosphatidylinositol (PtdIns)-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt) is a synthetic analog of natural PtdIns featuring saturated C16:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol stereochemistry as that of the natural compound. PtdIns-(3,5)-P2 is rapidly synthesized from PtdIns-(3)-P1 in yeast when a PtdIns-(3)-P5-hydroxy kinase is activated during hyperosmotic conditions.1 PtdIns-(3,5)-P2 is also present in mammalian cells, such as monkey COS-7 cells, where a similar biosynthetic route has been demonstrated.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Dove, S.K., Cooke, F.T., Douglas, M.R., et al. Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature 390, 187-192 (1997).