A cell signaling inositol phosphate intermediate.
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D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt)

Item No. 10008442

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
D-myo-inositol-1,3,4,6-tetrakis(dihydrogen phosphate), tetraammonium salt
CAS Number
142507-74-2
Synonyms
  • Ins(1,3,4,6)-P4
  • 1,3,4,6-IP4
Molecular Formula
C6H12O18P4 • 4NH4
Formula Weight
568.2
Purity
≥95%
Formulation (Request formulation change)
A lyophilized powder
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 50 mg/mlWater: 50 mg/ml
SMILES
O[C@H]1[C@H](OP([O-])(O)=[O+])[C@@H](OP([O-])(O)=O)[C@@H](O)[C@@H](OP([O-])(O)=O)[C@@H]1OP([O-])(O)=O.[NH4+].[NH4].[NH4+].[NH4+]
InChi Code
InChI=1S/C6H16O18P4.4H3N/c7-1-3(21-25(9,10)11)5(23-27(15,16)17)2(8)6(24-28(18,19)20)4(1)22-26(12,13)14;;;;/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20);4*1H3/t1-,2+,3?,4?,5?,6?;;;;
InChi Key
DOJNAPODMFHFNA-GUBBRYCUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 µg

    $63

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    500 µg

    $274

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    1 mg

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    Product Description

    D-myo-inositol-1,3,4,6-tetraphosphate(Ins(1,3,4,6)-P4) largely acts an intermediate, serving as substrate for inositol-1,3,4,6-tetraphosphate 5-kinase to produce inositol-1,3,4,5,6-pentaphosphate, or inositol-1,3,4,6-tetraphosphate 2-kinase to give inositol-1,2,3,4,6-pentaphosphate.1 These inositol pentaphosphates can be further phosphorylated to produce inositol-1,2,3,4,5,6-hexakisphosphate, or phytic acid, which serves diverse roles in eukaryotic tissues. Ins(1,3,4,6)-P4 is a poor activator of the inositol 1,4,5-trisphospate receptor in vitro.2 Other functions of this IP remain to be elucidated.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Raboy, V. Molecules of interest myo-inositol-1,2,3,4,5,6-hexakisphosphate. Phytochemistry 64, 1033-1043 (2003).

    2. Burford, N.T., Nahorski, S.R., Chung, S.K., et al. Binding and activity of the nine possible regioisomers of myo-inositol tetrakisphosphate at the inositol 1,4,5-trisphosphate receptor. Cell Calcium 21, 301-310 (1997).