Pure, synthetic inositol polyphosphate
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D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt)

Item No. 10008452

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
D-myo-inositol-1,2,4,5,6-penta(hydrogen phosphate), pentasodium salt
Synonyms
  • Ins(1,2,4,5,6)P5 (sodium salt)
  • 1,2,4,5,6-IP5 (sodium salt)
Molecular Formula
C6H12O21P5 • 5Na
Formula Weight
690.0
Purity
≥98%
Formulation (Request formulation change)
A lyophilized powder
Solubility(Learn about Variance in Solubility)
Water: 50 mg/ml
SMILES
O[C@H]1[C@@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@@H]1OP([O-])(O)=O.[Na+].[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C6H17O21P5.5Na/c7-1-2(23-28(8,9)10)4(25-30(14,15)16)6(27-32(20,21)22)5(26-31(17,18)19)3(1)24-29(11,12)13;;;;;/h1-7H,(H2,8,9,10)(H2,11,12,13)(H2,14,15,16)(H2,17,18,19)(H2,20,21,22);;;;;/q;5*+1/p-5/t1-,2?,3?,4?,5?,6?;;;;;
InChi Key
QSNOOIWNTRYOFK-HKUWTPFQSA-I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 µg

    $153

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    500 µg

    $235

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    1 mg

    $1,071

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    Product Description

    D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt) (Ins(1,2,4,5,6)P5 (sodium salt)) is one of several different inositol oligophosphate isomers implicated in signal transduction. In human Jurkat T-lymphocytes, as well as in cytosolic extracts from fetal calf thymus, Ins(1,2,4,5,6)P5 (sodium salt) is phosphorylated by a 1/3 kinase to InsP6.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rudolf, M.T., Kaiser, T., Guse, A.H., et al. Synthesis and metabolism of the myo-inositol pentakisphosphates. Liebigs Annalen 1861-1869 (1997).

    2. Guse, A.H., and Emmrich, F. T-cell receptor-medicated metabolism of inositol polyphosphates in Jurkat T-lymphocytes. The Journal of Biological Chemisty 266(36), 24498-24502 (1991).