A novel fatty acid amide
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Lauric Acid Leelamide

Item No. 10008618

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]-dodecanamide
CAS Number
2095306-47-9
Molecular Formula
C32H53NO
Formula Weight
467.8
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 20 mg/ml
SMILES
CC(C)C(C=C1)=CC2=C1[C@]3(C)[C@](CC2)([H])[C@](C)(CNC(CCCCCCCCCCC)=O)CCC3
InChi Code
InChI=1S/C32H53NO/c1-6-7-8-9-10-11-12-13-14-16-30(34)33-24-31(4)21-15-22-32(5)28-19-17-26(25(2)3)23-27(28)18-20-29(31)32/h17,19,23,25,29H,6-16,18,20-22,24H2,1-5H3,(H,33,34)/t29-,31-,32+/m0/s1
InChi Key
ZJZPELRZWMRYGW-RUHGTMQNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $68

    Add

    10 mg

    $124

    Add

    50 mg

    $515

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Lauric acid leelamide is the lauric (C-12) amide analog of leelamine. Leelamine has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM.1 Leelamine inhibits pyruvate dehydrogenase kinase (PDHK) with an IC50 value of 9.5 µM.2 Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of phospholipase A2 activity from a variety of sources.3 There are no published studies of the pharmacological properties of lauric acid leelamide.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Martin, B.R. Leelamine. (2006).

    2. Aicher, T.D., Damon, R.E., Koletar, J., et al. Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK). Bioorg. Med. Chem. Lett. 9(15), 2223-2228 (1999).

    3. Wilkerson, W., DeLucca, I., Galbraith, W., et al. Antiinflammatory phospholipase-A2 inhibitors. Eur. J. Med. Chem. 26(7), 667-676 (1991).