A thiol-specific biotinylating reagent
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3-(N-Maleimidopropionyl)-biocytin

Item No. 10008879

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N2-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-N6-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-L-lysine
CAS Number
102849-12-7
Synonyms
  • MPB
Molecular Formula
C23H33N5O7S
Formula Weight
523.6
Purity
≥80%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 2 mg/mlPBS (pH 7.2): 0.2 mg/ml
λmax
205 nm
SMILES
[H]N1[C@@]2([H])[C@@](CS[C@H]2CCCCC(N([H])CCCC[C@H](NC(CCN3C(C=CC3=O)=O)=O)C(O)=O)=O)([H])N([H])C1=O
InChi Code
InChI=1S/C23H33N5O7S/c29-17(7-2-1-6-16-21-15(13-36-16)26-23(35)27-21)24-11-4-3-5-14(22(33)34)25-18(30)10-12-28-19(31)8-9-20(28)32/h8-9,14-16,21H,1-7,10-13H2,(H,24,29)(H,25,30)(H,33,34)(H2,26,27,35)/t14?,15-,16-,21-/m0/s1
InChi Key
KWNGAZCDAJSVLC-AKCVKGCPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $25

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    5 mg

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    10 mg

    $88

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    50 mg

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    Product Description

    3-(N-Maleimidopropionyl)-biocytin (MPB) is a versatile thiol-specific biotinylating reagent. It is specific for sulfhydryl groups or reduced disulfide bonds and will not label proteins lacking a free sulfhydryl group at a pH between 6.5 and 7.5. This probe can be used in combination with the appropriate avidin- or streptavidin-conjugated markers (i.e., fluorescent, enzyme-conjugated, etc.). MPB can be used to detect protein sulfhydryl groups on dot blots with sensitivities in the femtomole range.1 MPB can be utilized for cell sorting, enzyme immunoassay, protein blotting, and various cytochemical procedures.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bayer, E.A., Zalis, M.G., and Wilchek, M. 3-(N-maleimido-propionyl) biocytin: A versatile thiol-specific biotinylating reagent. Anal. Biochem. 149, 529-536 (1985).