A PPARα and PPARγ dual agonist
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CAY10514

Item No. 10009017

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
8-hydroxy-8-[2-(pentyloxy)phenyl]-5-octynoic acid, methyl ester
CAS Number
868526-38-9
Synonyms
  • Methyl-8-hydroxy-8-(2-pentyl-oxyphenyl)-oct-5-ynoate
Molecular Formula
C20H28O4
Formula Weight
332.4
Purity
≥98%
Formulation
A 10 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
λmax
220, 272 nm
SMILES
CCCCCOC1=CC=CC=C1C(O)CC#CCCCC(OC)=O
InChi Code
InChI=1S/C20H28O4/c1-3-4-11-16-24-19-14-10-9-12-17(19)18(21)13-7-5-6-8-15-20(22)23-2/h9-10,12,14,18,21H,3-4,6,8,11,13,15-16H2,1-2H3
InChi Key
ZQRYAWVNSTVEIJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $28

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    5 mg

    $118

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    10 mg

    $205

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    50 mg

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    Product Description

    CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPARα and PPARγ with EC50 values of 0.173 and 0.642 µM, respectively.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Caijo, F., Mosset, P., Grée, R., et al. Synthesis of aromatic analogs of 8(S)-HETE and their biological evaluation as activators of the PPAR nuclear receptors. The Journal of Organic Chemistry 2006(9), 2181-2196 (2006).