A PPARγ agonist
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CAY10506

Item No. 10009079

Technical Information
Formal Name
N-[2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]ethyl]-1,2-dithiolane-3-pentanamide
CAS Number
292615-75-9
Molecular Formula
C20H26N2O4S3
Formula Weight
Purity
≥98%
Formulation
A 10 mg/ml solution in methyl acetate
DMF: 5 mg/mlDMSO: 5 mg/mlDMSO:PBS(pH 7.2) (1:5): 0.15 mg/mlEthanol: 3 mg/ml
SMILES
O=C(CCCCC1SSCC1)NCCOc1ccc(cc1)CC1SC(=O)NC1=O
InChi Code
InChI=1S/C20H26N2O4S3/c23-18(4-2-1-3-16-9-12-27-29-16)21-10-11-26-15-7-5-14(6-8-15)13-17-19(24)22-20(25)28-17/h5-8,16-17H,1-4,9-13H2,(H,21,23)(H,22,24,25)
InChi Key
VDWFJOXRKJFJMP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    CAY10506 is a hybrid lipoic acid-TZD derivative that transactivates human PPARγ with an EC50 value of 10 µM.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chittiboyina, A.G., Venkatraman, M.S., Mizuno, C.S., et alDesign and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARγ agonists. J. Med. Chem. 49(14), 4072-4084 (2006).