For immunochemical detection of Ribosomal S6 Kinase 2
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Ribosomal S6 Kinase 2 Polyclonal Antibody

Item No. 10009411

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • RSK2
Immunogen
Peptide from the C-terminal region of rat RSK2
Formulation (Request formulation change)
100 µl of peptide affinity-purified antibody
Storage Buffer
10 mM HEPES, pH 7.5, containing 150 nM sodium chloride, 100 µg BSA/ml and 50% glycerol
Host
Rabbit
Applications
WB
Species Reactivity
(+) Rat RSK2(+) Bovine RSK2 (expected)(+) Canine RSK2 (expected)(+) Chicken RSK2 (expected)(+) Human RSK2 (expected)(+) Mouse RSK2 (expected)
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    1 ea

    $464

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    Product Description

    The p90 ribosomal S6 kinases (RSKs) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits.1 Recent work suggests that RSK2 exerts a tonic regulation on G protein-coupled signaling.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hanauer, A., and Young, I.D. Coffin-Lowry syndrome: Clinical and molecular features. J. Med. Genet. 39, 705-713 (2002).

    2. Sheffler, D.J., Kroeze, W.K., Garcia, B.G., et al. p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling. Proc. Natl. Acad. Sci. USA 103, 4717-4722 (2006).