A lysophosphatidic acid analog
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

1-Palmitoyl-2-hydroxy-sn-glycero-3-PA

Item No. 10010094

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
hexadecanoic acid, 2R-hydroxy-3-(phosphonooxy)propyl ester
CAS Number
7220-34-0
Synonyms
  • 1-Hexadecanoyl-2-hydroxy-sn-glycero-3-phosphate
  • 16:0 LPA
  • LPA 16:0
  • PA(16:0/0:0)
  • 1-Palmitoyl LPA
  • 1-Palmitoyl Lysophosphatidic Acid
Molecular Formula
C19H39O7P
Formula Weight
410.5
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Ethanol: Soluble: ≥10mg/mlEthanol:PBS (pH 7.2) (1:9): Slightly soluble: 0.1-1mg/ml
SMILES
CCCCCCCCCCCCCCCC(OC[C@@H](O)COP(O)(O)=O)=O
InChi Code
InChI=1S/C19H39O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24/h18,20H,2-17H2,1H3,(H2,22,23,24)/t18-/m1/s1
InChi Key
YNDYKPRNFWPPFU-GOSISDBHSA-N
Side Chain Carbon Sum
16:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $43

    Add

    5 mg

    $150

    Add

    10 mg

    $257

    Add

    25 mg

    $534

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    1-Palmitoyl-2-hydroxy-sn-glycero-3-PA (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.1,2 Additionally, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Noguchi, K., Ishii, S., and Shimizu, T. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family. The Journal of Biological Chemisty 278(28), 25600-25606 (2003).

    2. Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions. Trends Cell Biol. 4(6), 213-219 (1994).

    3. Krogfelt, K.A., Utley, M., Krivan, H.C., et al. Specific phospholipids enhance the activity of β-lactam antibiotics against Pseudomonas aeruginosa. J. Antimicrob. Chemother. 46(3), 377-384 (2000).