A lipophilic analog of 17-phenyl trinor PGF2α
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17-phenyl trinor Prostaglandin F2α methyl ester

Item No. 10010110

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
7-[3R,5S-dihydroxy-2R-[3S-hydroxy-5Z-phenyl-1R-penten-1E-yl]cyclopentyl]-5-heptenoic acid, methyl ester
CAS Number
38315-47-8
Synonyms
  • Bimatoprost methyl ester
  • 17-phenyl trinor PGF2α methyl ester
Molecular Formula
C24H34O5
Formula Weight
402.5
Purity
≥98%
Formulation
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
Acetonitrile: 3 mg/mlDMF: 25 mg/mlDMSO: 25 mg/mlEthanol: 50 mg/mlPBS (pH 7.2): .25 mg/ml
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(OC)=O)[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1
InChi Code
InChI=1S/C24H34O5/c1-29-24(28)12-8-3-2-7-11-20-21(23(27)17-22(20)26)16-15-19(25)14-13-18-9-5-4-6-10-18/h2,4-7,9-10,15-16,19-23,25-27H,3,8,11-14,17H2,1H3/b7-2-,16-15+/t19-,20+,21+,22-,23+/m0/s1
InChi Key
UQBYFURYGYNQLQ-FDBOBMRISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $81

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    5 mg

    $357

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    10 mg

    $633

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    Product Description

    Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. 17-phenyl trinor PGF2α methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α.1 Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Balapure, A.K., Rexroad, C.E., Jr., Kawada, K., et al. Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2α receptor. Biochem. Pharmacol. 38(14), 2375-2381 (1989).