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(+)-Cloprostenol methyl ester

Item № 10010115
CAS № 56687-85-5
Purity ≥98%
product image
                (CAS 56687-85-5)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 mg $58.00 0.00
     5 mg $261.00 0.00
     10 mg $464.00 0.00

Pricing updated 2019-07-18. Prices are subject to change without notice.

Description
Synonyms
  • D-Cloprostenol methyl ester
  • (+)-16-m-Chlorophenoxy tetranor PGF methyl ester

(+)-Cloprostenol is a synthetic analog of prostaglandin F (PGF). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF.1 Cloprostenol is also used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (+)-Cloprostenol methyl ester is a more lipid soluble form of cloprostenol, which may be more amenable for certain formulations.

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Technical Information
Formal Name
(+)-9α,11α,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, methyl ester
CAS Number
56687-85-5
Synonyms
  • D-Cloprostenol methyl ester
  • (+)-16-m-Chlorophenoxy tetranor PGF methyl ester
Molecular Formula
C23H31ClO6
Formula Weight
438.9
Purity
≥98%
Formulation
A solution in ethanol
λmax
220, 275, 282 nm
SMILES
ClC1=CC(OC[C@H](O)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(OC)=O)=CC=C1
InChI Code
InChI=1S/C23H31ClO6/c1-29-23(28)10-5-3-2-4-9-19-20(22(27)14-21(19)26)12-11-17(25)15-30-18-8-6-7-16(24)13-18/h2,4,6-8,11-13,17,19-22,25-27H,3,5,9-10,14-15H2,1H3/b4-2-,12-11+/t17-,19-,20-,21+,22-/m1/s1
InChI Key
DVBATKLFQCCUII-OWEKAKITSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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References & Product Citations
Product Description References

1. Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F Nature 250(464), 330-331 (1974).

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