A saturated fatty acid
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Palmitate (calcium salt)

Item No. 10010279

Technical Information
Formal Name
hexadecanoic acid, calcium salt
CAS Number
542-42-7
Synonyms
  • Calcium palmitate
  • FA 16:0
Molecular Formula
[C16H31O2]2 • Ca
Formula Weight
Purity
>98%
A crystalline solid
Chloroform: 0.3 mg/ml
SMILES
CCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCC([O-])=O.[Ca+2]
InChi Code
InChI=1S/2C16H32O2.Ca/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18;/h2*2-15H2,1H3,(H,17,18);/q;;+2/p-2
InChi Key
HRBZRZSCMANEHQ-UHFFFAOYSA-L
Side Chain Carbon Sum
16:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Saturated fatty acids are synthesized by both plants and animals from acetyl coenzyme A as a form of long-term energy storage. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of the normal dietary fat intake. Palmitic acid also makes up approximately 25% of the total plasma fatty acids in plasma lipoproteins.1 Saturated free fatty acids induce the expression of cyclooxygenase 2,2 and after protein acylation, are used to confer lipid anchoring to a variety of signaling molecules.3,4,5,6 Palmitate is the salt (in this case calcium) of palmitic acid. It is this anion that is observed at physiological pH. Calcium palmitate is one of the major components of gallstones.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Santos, M.J., López-Jurado, M., Llopis, J., et alInfluence of dietary supplementation with fish oil on plasma fatty acid composition in coronary heart disease patients. Ann. Nutr. Metab. 39(1), 52-62 (1995).

    2. Lee, J.Y., Sohn, K.H., Rhee, S.H., et alSaturated fatty acids, but not unsaturated fatty acids, induced the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. The Journal of Biological Chemisty 276(20), 16683-16689 (2001).

    3. Dietzen, D.J., Hastings, W.R., and Lublin, D.M. Caveolin is palmitoylated on multiple cysteine residues. Palmitoylation is not necessary for localization of caveolin to caveolae. The Journal of Biological Chemisty 270(12), 6838-6842 (1995).

    4. Robinson, L.J., and Michel, T. Mutagenesis of palmitoylation sites in endothelial nitric oxide synthase identifies a novel motif for dual acylation and subcellular targeting. Proc. Natl. Acad. Sci. USA 92(25), 11776-11780 (1995).

    5. Topinka, J.R., and Bredt, D.S. N-terminal palmitoylation of PSD-95 regulates association with cell membranes and interaction with K+ channel Kv1.4. Neuron 20(1), 125-134 (1998).

    6. Miggin, S.M., Lawler, O.A., and Kinsella, B.T. Palmitoylation of the human prostacyclin receptor. Functional implications of palmitoylation and isoprenylation. The Journal of Biological Chemisty 278(9), 6947-6958 (2003).