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(+)-Cloprostenol methyl amide

Item № 10010495
Purity ≥98%
product image
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 mg $58.00 0.00
     5 mg $261.00 0.00
     10 mg $464.00 0.00

Pricing updated 2019-07-18. Prices are subject to change without notice.

Description
Synonyms
  • D-Cloprostenol methyl amide
  • (+)-16-m-Chlorophenoxy tetranor PGF methyl amide

(+)-Cloprostenol is a synthetic analog of prostaglandin F (PGF). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF.1 Cloprostenol is also used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (+)-Cloprostenol methyl amide is a more lipid soluble form of (+)-cloprostenol. Amides of PGs may serve as prodrugs, under the condition they are hydrolyzed appropriately in certain tissues to generate the bioactive free acid.

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Technical Information
Formal Name
(+)-9α,11α,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, methyl amide
Synonyms
  • D-Cloprostenol methyl amide
  • (+)-16-m-Chlorophenoxy tetranor PGF methyl amide
Molecular Formula
C23H32ClNO5
Formula Weight
438.0
Purity
≥98%
Formulation
A solution in ethanol
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(NC)=O)[C@@H](/C=C/[C@@H](O)COC2=CC=CC(Cl)=C2)[C@H](O)C1
InChI Code
InChI=1S/C23H32ClNO5/c1-25-23(29)10-5-3-2-4-9-19-20(22(28)14-21(19)27)12-11-17(26)15-30-18-8-6-7-16(24)13-18/h2,4,6-8,11-13,17,19-22,26-28H,3,5,9-10,14-15H2,1H3,(H,25,29)/b4-2-,12-11+/t17-,19-,20-,21+,22-/m1/s1
InChI Key
IFOQFZVPFCRSLM-OWEKAKITSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
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Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F Nature 250(464), 330-331 (1974).

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