A pH-controlled nitric oxide donor
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Product Categories

Product Type

Biochemicals
Nitric Oxide Donors

Research Area

CAY10565

Item No. 10010528

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-methoxy-4-phenyl-1,3,2-oxathiazolidine-5-one
Synonyms
  • 4-(p-methoxyphenyl)-1,3,2-Oxathiazolylium-5-olate
Molecular Formula
C9H9NO3S
Formula Weight
211.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/mlEthanol: 0.25 mg/ml
λmax
202, 268, 436 nm
SMILES
COc1ccc(cc1)C1[S]=NOC1O
InChi Code
InChI=1S/C9H9NO3S/c1-12-7-4-2-6(3-5-7)8-9(11)13-10-14-8/h2-5,8-9H,1H3
InChi Key
OUCJPOXOGCRTEY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $36

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    10 mg

    $68

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    25 mg

    $153

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    100 mg

    $469

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    Product Description

    CAY10565 is a member of a new class of S-nitrosothiol species that act as NO donors under acidic conditions. It decomposes with a half-life of 130 minutes in 0.1 M phosphate buffer, pH 5.0, at 37°C and relaxes phenylephrine-constricted rat aortic strips 71% and 44% at pH 6.0 and 7.4, respectively.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lu, D., Nadas, J., Zhang, G., et al. 4-Aryl-1,3,2-oxathiazolylium-5-olates as pH-controlled NO-donors: The next generation of S-nitrosothiols. J. Am. Chem. Soc. 129(17), 5503-5514 (2007).