An analog of Prostaglandin F
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17-phenoxy trinor Prostaglandin F

Item No. 10010839

Technical Information
Formal Name
(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenoxy-1-penten-1-yl]cyclopentyl]-5-heptenoic acid
CAS Number
2162157-41-5
Synonyms
  • 17-phenoxy trinor PGF
Molecular Formula
C23H32O6
Formula Weight
Purity
≥98%
Formulation
A 10 mg/ml solution in methyl acetate
DMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
OC(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCOc1ccccc1
InChi Code
InChI=1S/C23H32O6/c24-17(14-15-29-18-8-4-3-5-9-18)12-13-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,12-13,17,19-22,24-26H,2,7,10-11,14-16H2,(H,27,28)/b6-1-,13-12+/t17-,19-,20-,21+,22-/m1/s1
InChi Key
UUTUTDVOWPRLDV-GESHSCTDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    17-phenoxy trinor prostaglandin F (17-phenoxy trinor PGF) is a novel analog of PGF. A similar analog, 16-phenoxy tetranor PGF, binds to the FP receptor on luteal cells with much greater affinity (440%) than PGF.1 There are no published reports on the biological activity of 17-phenoxy trinor PGF.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Balapure, A.K., Rexroad, C.E., Jr., Kawada, K., et alStructural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F receptor. Biochem. Pharmacol. 38(14), 2375-2381 (1989).