Starting material for inhibitors of glucosylceramide synthase
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Deoxynojirimycin Tetrabenzyl Ether

Item No. 10011914

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3R,4R,5S-tris(phenylmethoxy-2R-[(phenylmethoxy)methyl]-piperidine
CAS Number
69567-11-9
Synonyms
  • DNJ Tetrabenzyl Ether
  • dNM Tetrabenzyl Ether
Molecular Formula
C34H37NO4
Formula Weight
523.7
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 15 mg/mlDMSO: 20 mg/mlDMSO:PBS(pH7.2) 1:1: 0.5 mg/mlEthanol: 0.25 mg/ml
SMILES
c1ccc(cc1)CO[C@@H]1[C@@H](COCc2ccccc2)NC[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1
InChi Code
InChI=1S/C34H37NO4/c1-5-13-27(14-6-1)22-36-26-31-33(38-24-29-17-9-3-10-18-29)34(39-25-30-19-11-4-12-20-30)32(21-35-31)37-23-28-15-7-2-8-16-28/h1-20,31-35H,21-26H2/t31-,32+,33-,34-/m1/s1
InChi Key
HHIIDKLQTCPFQA-KMKAFXEASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $82

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    10 mg

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    25 mg

    $263

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    50 mg

    $486

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    Product Description

    Deoxynojirimycin (dNM) tetrabenzyl ether is an intermediate for the synthesis of glucosylceramide synthase inhibitors such as 1-dNM, a glucose analog that potently inhibits α-glucosidase I and II.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Matos, C.R.R., Lopes, R.S.C., and Lopes, C.C. Synthesis of 1-deoxynojirimycin and N-butyl-1-deoxynojirimycin. Synthesis 4, 571-573 (1999).