Oxidized form of ebselen, lacking antioxidant activity
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Ebselen Oxide

Item No. 10012298

Technical Information
Formal Name
1-oxide-2-phenyl-1,2-benzisoselenazol-3(2H)-one
CAS Number
104473-83-8
Synonyms
  • NSC 639772
Molecular Formula
C13H9NO2Se
Formula Weight
Purity
≥95%
A crystalline solid
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 5 mg/mlPBS (pH 7.2): .15 mg/ml
λmax
281 nm
SMILES
O=[Se](N1C2=CC=CC=C2)C3=CC=CC=C3C1=O
InChi Code
InChI=1S/C13H9NO2Se/c15-13-11-8-4-5-9-12(11)17(16)14(13)10-6-2-1-3-7-10/h1-9H
InChi Key
SBTLFLABILGUMK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Ebselen is an excellent scavenger of peroxynitrite and is used for the treatment of cerebral infarctions. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, indicating that it can serve as a negative control for ebselen.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lass, A., Witting, P., Stocker, R., et alInhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: Antioxidant actions in addition to hydroperoxide-reducing activity. Biochim. Biophys. Acta 1303, 111-118 (1996).